Browsing by Subject "A61K 39/085"

Now showing items 1-9 of 9

    • Compositions And Use Of A Fibrinogen Binding Motif Present In EFB And COA For Therapeutics And Vaccines Against Staphylococcus Aureus 
      Koo, Ya-Ping; Hook, Magnus; Arora, Srishtee; Visai, Livia; Bertoglio, Federico; Hust, Michael; Meier, Doris (United States. Patent and Trademark Office; Texas A&M University. Libraries, 8/9/2022)
      The present disclosure provides methods and composition including vaccines, monoclonal antibodies, polyclonal antibodies, chimeric molecule of an extracellular fibrinogen binding protein (Efb) and targeted agent delivery ...
    • Cross-reactive displacing antibodies from collagen-binding proteins and method of identification and use 
      Hook, Magnus; Xu, Yi; Speziale, Pietro; Visal, Livia; Casolini, Fabrizia; Patti, Joseph M.; Patel, Pratiksha; Domanski, Paul (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2007-07-10)
      Antibodies to the CNA protein and to other regions from the collagen binding domain, including domain CNA19, are provided, and antibodies produced in this manner have been shown to be cross reactive to both Staphylococcus ...
    • Fibronectin binding protein compositions and methods of use 
      Hook,Magnus; Patti, Joseph M.; House-Pompeo, Karen L.; Speziale, Pietro; Joh, Danny; Mcgavin, Martin J. (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2004-02-03)
      Disclosed are antibodies that block the binding of fibronectin protein to fibronectin. Also disclosed are site specifically-mutated and truncated peptide epitopes derived from the fnbA and fnbB genes of Staphylococcus ...
    • Fibronectin binding protein compositions and methods of use 
      Hook, Magnus; Patti, Joseph M.; House-pompeo, Karen L.; Speziale, Pietro; Joh, Danny; Mcgavin, Martin J. (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2006-10-31)
      Disclosed are antibodies that block the binding of fibronectin protein to fibronectin. Also disclosed are site specifically-mutated and truncated peptide epitopes derived from the fnbA and fnbB genes of Staphylococcus ...
    • Multicomponent vaccines 
      Patti, Joseph M.; Foster, Timothy J.; Hook, Magnus (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2010-02-23)
      Multicomponent vaccines are provided which aid in the prevention and treatment of staphylococcal infections and which include certain selected combinations of bacterial binding proteins or fragments thereof, or antibodies ...
    • Multicomponent vaccines 
      Patti, Joseph M.; Foster, Timothy J.; Hook, Magnus (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2004-03-09)
      Multicomponent vaccines are provided which aid in the prevention and treatment of staphylococcal infections and which include certain selected combinations of bacterial binding proteins or fragments thereof, or antibodies ...
    • Multicomponent vaccines 
      Patti, Joseph M.; Foster, Timothy J.; Hook, Magnus (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2011-09-13)
      Multicomponent vaccines are provided which aid in the prevention and treatment of staphylococcal infections and which include certain selected combinations of bacterial binding proteins or fragments thereof, or antibodies ...
    • Targeting Of Ligand Binding Sites In ClfA 
      Ganesh, Vannakambadi K.; Hook, Magnus (United States. Patent and Trademark Office; Texas A&M University. Libraries, 9/20/2022)
      The present invention provides methods and compositions to reduce binding of fibrinogen to the ClfA in a gram positive bacterial infections using monoclonal antibody, a polyclonal antibody, an antigen-binding antibody ...
    • Treatment of Staphylococcus aureus infections utilizing antibodies that bind to fibronectin binding proteins 
      Hook, Magnus; Patti, Joseph M.; House-pompeo, Karen L.; Speziale, Pietro; Joh, Danny; Mcgavin, Martin J. (United States. Patent and Trademark Office; Texas A&M University. Libraries, 2012-07-03)
      Disclosed are antibodies that block the binding of fibronectin protein to fibronectin. Also disclosed are site specifically-mutated and truncated peptide epitopes derived from the fnbA and fnbB genes of Staphylococcus ...